Techniques in Protein Biosynthesis

نویسنده

  • Sherman M. Weissman
چکیده

This book is volume 2 in a series intended to introduce methods used in the study of protein biosynthesis. The present volume includes chapters on the genetic approach to the study of protein biosynthesis in plant systems, analysis of polysomes, fractionation of ribosomal proteins, animal operative techniques, and the use of sources of high energy phosphate. Inevitably, there is overlap with standard works, such as Methods in Enzymology. However, this volume contains much valuable material that supplements and complements other standard texts. The chapter by Hans Noll on the analysis of the structure and function of polysomes contains a detailed and exact description of the well thoughtout approaches used in the author's laboratory, and is valuable reading for students of biochemistry of all ages. The chapter on animal operative techniques is brief but informative for someone not particularly involved in this work. The chapter on protein biosynthesis gives a fairly extensive introduction to this area. The chapter on the genetic approach to protein biosynthesis is a very brief overview of the field that could well occupy a large volume itself. Also, inevitably, it does not contain much of the newest advances in fundamental understanding of this area. Nevertheless, it is a chapter that would be particularly valuable for students taking an introductory course in molecular biology or biochemistry. The chapter on fractionation of ribosomal proteins was informative but did not include a discussion of the recent substantial advances in fractionation and characterization of E. coli, and as such, is somewhat out of date. Overall, this is a valuable reference volume to have for workers in this field, and certain of the chapters would be recommended for reading in graduate courses in biochemistry and molecular biology. from the second edition of Ovulationshemitmung durch Hormone. During the mid-1960's it was common for pharmaceutical houses to put out contraceptive pills that were virtually the same as other successful medications produced by competing firms. In many instances this did not necessarily add to the competence of contraception control but rather allowed sharing of a market that was so financially attractive. Very little difference, if any, could be noted among the various preparations that stampeded into public domain. A similar situation exists now in books describing hormonal contraception. A case in point is Hormnonal Contraception , by Jiirgen Haller, which reviews the subject of hormonal contraceptives primarily from the point of view of steroidal inhibition …

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عنوان ژورنال:
  • The Yale Journal of Biology and Medicine

دوره 43  شماره 

صفحات  -

تاریخ انتشار 1970